/spandiv style="width:464px;font-size:13px;font-weight:400;font-style:normal;line-height:16px;" img src="http://news.bbcimg.co.uk/media/images/53850000/jpg/_53850959_daniel_danielle.jpg" width="464" height="261" alt="Danielle and Daniel"span style="width:464px;display:inline-block;"Danielle and Daniel are one of only a handful of couples using Pre-Implantation Genetic Diagnosis (PGD) on the NHS to screen out the breast cancer gene/span /div div class="story-feature related narrow"Related Stories/div p class="introduction" id="story_continues_1"New genetic treatments can help couples ensure their baby will not inherit family diseases such as cancer but, as Adam Wishart explains, advances in science bring with them new dilemmas. /p pA year ago, in South Shields, teacher Daniel Stanley faced one of the toughest things for a brother - watching his younger sister Natasha die of breast cancer at the tender age of 28. /p div style="width:280px;float:right;clear:right;font-size:13px;text-align:right;margin-right:20px;"blockquote style="font-weight:bold;font-size:16px;"p class="first-child"ldquo;There is a risk. If we select out all the embryos that have these mutations then we might be selecting out some of the best people in society. rdquo;/p/blockquotespan class="quote-credit"Professor Michael Baum/span span class="quote-credit-title"Researcher on breast cancer/span /div p id="story_continues_2""It is hard to watch someone like that. Optimistic one minute, and then to receive another diagnosis," said Daniel./p pAs Natasha died, she discovered that the cancer had a genetic basis on one of two breast cancer genes, BRCA1 and BRCA2. /p pDaniel was also tested and found out that he had the same gene. /p pIt placed him on the horns of a very difficult dilemma because he wanted children, but did not want to pass on the gene. /ppThrough his genetic counsellors, he and his partner Danielle were offered Pre-Implantation Genetic Diagnosis (PGD) - a technique which screens IVF embryos for genetic disorders./p pWhen the embryos are only eight cells large, an embryologist very carefully makes a hole in each shell, and sucks out a single cell to be tested genetically. /p div class="story-feature wide "Find out morediv style="float:right;width:305px;display:inline;font-size:13px;font-weight:400;font-style:normal;line-height:16px;" img src="http://news.bbcimg.co.uk/media/images/53843000/jpg/_53843513_adam_wishart_bbc.jpg" width="304" height="171" alt="Adam Wishart" /divWhen the mother of director Adam Wishart died of cancer he decided to find out if there was a family cancer gene, and if there would be any benefit to knowing.Should I Test My Genes? The Price of Life will be on BBC Two at 2100 BST on Tuesday 5 July 2011./div p id="story_continues_3"Any that are free of the faulty gene are transferred into the mother's womb. /p pPGD has been offered by the NHS for more than a decade for serious diseases that come early in childhood, like cystic fibrosis or Tay Sachs, a neurological disease./p pBut for a treatable adult disease the ethics are debatable, and so the first child free of the breast cancer gene by PGD was born only in 2009./p pThere are some that argue that by using PGD for these diseases Britain is taking a step onto a dangerous slippery slope. /ppProfessor Michael Baum, a leading researcher in breast cancer, is doubtful whether PGD should be used for inherited breast cancer./p p"There is a phenomena in genetics and cellular development called co-expression in which two genes can be stuck together," he said./p p"If you have the mutant gene, that might be co-expressed with favourable components of the human genome. /p p"So if you breed out the BRCA1 and BRCA2 mutation you may inadvertently breed out something of value. /p p"Just say it is the gene or the complex of genes for beauty, or say it is a complex of genes for high intelligence. /p p"There is a risk. If we select out all the embryos that have these mutations then we might be selecting out some of the best people in society. /p p"Now you think that is facetious. It may not be beauty and intelligence but it may be something else that has an evolutionary advantage."/p pPioneers/p div style="float:right;width:305px;display:inline;font-size:13px;font-weight:400;font-style:normal;line-height:16px;" img src="http://news.bbcimg.co.uk/media/images/53850000/jpg/_53850961_natasha.jpg" width="224" height="299" alt="Natasha "span style="width:224px;display:inline-block;"Daniel's sister Natasha died from breast cancer at just 28 years old/span /div pDespite the arguments, Daniel and Danielle have decided to become part of the pioneers for breast cancer. /p p"I think I'd feel a lot less comfortable with the idea if we were being more selective - if we were saying we wanted a boy or a girl," said Daniel. /p pDanielle said: "We are not changing the genes, we are just selecting the embryos without a cancer gene. /p p"The other option we were given was to conceive naturally and then to have a gender test and then have a termination if it was a girl. I couldn't do that."/p pDaniel feels that having watched his sister, preventing that kind of suffering is almost a kind of duty./p p"If science has given me that power to do something about it then really I should use that power. That is something that the human race has created - it is part of the history of our progress and that is an opportunity really."/p pDaniel and Danielle hope to go through PGD later in the year at Guy's hospital in London./p pa href="http://www.bbc.co.uk/programmes/b012g0cc" title="Should I Test My Genes The Price of Life"Should I Test My Genes? The Price of Life/a will be on BBC Two at 2100 BST on Tuesday 5 July 2011 and after on a href="http://www.bbc.co.uk/iplayer/"BBC iPlayer/a (UK only)/ppThis article is from the a href="http://news.bbc.co.uk" title="Link to BBC News"BBC News website/a. © British Broadcasting Corporation, The BBC is not responsible for the content of external internet sites./pdiv class="feedflare" a href="http://feeds.feedburner.com/~ff/bbcnewshealthfullfeed?a=2MESMJTTqPc:0rBt0ZpOSJ8:yIl2AUoC8zA"img src="http://feeds.feedburner.com/~ff/bbcnewshealthfullfeed?d=yIl2AUoC8zA" border="0"/img/a a href="http://feeds.feedburner.com/~ff/bbcnewshealthfullfeed?a=2MESMJTTqPc:0rBt0ZpOSJ8:F7zBnMyn0Lo"img src="http://feeds.feedburner.com/~ff/bbcnewshealthfullfeed?i=2MESMJTTqPc:0rBt0ZpOSJ8:F7zBnMyn0Lo" border="0"/img/a a href="http://feeds.feedburner.com/~ff/bbcnewshealthfullfeed?a=2MESMJTTqPc:0rBt0ZpOSJ8:V_sGLiPBpWU"img src="http://feeds.feedburner.com/~ff/bbcnewshealthfullfeed?i=2MESMJTTqPc:0rBt0ZpOSJ8:V_sGLiPBpWU" border="0"/img/a /divimg src="http://feeds.feedburner.com/~r/bbcnewshealthfullfeed/~4/2MESMJTTqPc" height="1" width="1"/